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How to pronounce methotrexate

Say it like meth-uh-TREK-sayt. Methotrexate has four syllables, and the main stress falls on the third one (TREK).

VoiceSpeed

Click the play button next to American or British to hear how to pronounce methotrexate. Choose Slow to hear each sound clearly.

US American/ˌmɛθəˈtrɛkˌseɪt/meth-uh-TREK-sayt
UK British/ˌmɛθəˈtrɛkseɪt/meth-uh-TREK-sayt
  • meth
  • uh
  • TREK
  • sayt
  • Main stress
  • Lighter stress
  • Unstressed

Methotrexate pronunciation, sound by sound

Read the parts left to right, then blend them together without pausing.

  1. methGive this part a little weight. The vowel is the "e" in bed.
  2. uhKeep this part quick and light. The vowel is the relaxed "uh" in about.
  3. TREKSay this part loudest and longest. The vowel is the "e" in bed.
  4. saytGive this part a little weight. The vowel is the "ay" in day.

American vs British pronunciation of methotrexate

American and British speakers say methotrexate in essentially the same way: /ˌmɛθəˈtrɛkˌseɪt/ in the US and /ˌmɛθəˈtrɛkseɪt/ in the UK.

British respelling: meth-uh-TREK-sayt.

What does methotrexate mean?

noun
  1. An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies.

Where does methotrexate come from?

Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate.

Questions about saying methotrexate

How do you pronounce methotrexate?

Say meth-uh-TREK-sayt. The American pronunciation is /ˌmɛθəˈtrɛkˌseɪt/. In British English it is /ˌmɛθəˈtrɛkseɪt/. Press play above to hear it at normal speed or slowly.

How many syllables are in methotrexate?

Methotrexate has four syllables, and the main stress falls on the third one (TREK). Broken into parts: meth · uh · TREK · sayt.

Do Americans and Brits say methotrexate the same way?

Almost exactly. The American form is /ˌmɛθəˈtrɛkˌseɪt/ and the British form is /ˌmɛθəˈtrɛkseɪt/, so you can use either pronunciation with any listener.

Pronunciation from Wiktionary; meaning and origin adapted from Wiktionary (CC BY-SA 4.0).